I've been in your shoes; not pleasant. Try unmounting your media drive and see if it opens. If your media is held locally, change the folder's name temporarily, then launch. You might also try deleting video preview files. These steps could help you isolate a corrupt media file or a bad render file.
As a troubleshooting step, you can try a clean (under Custom) reinstall of the 528.24 studio drivers (not the game-ready ones). Using Adobe Cleaner and then reinstalling can work.
Otherwise, it might be a corrupt project file, and you'd have to resort to a backup file. Do you save backups as a part of your workflow? If not, do you have any backups in your Auto Save folder? Check the Creative Cloud folder for a backup (if you chose that preference in Auto Save preferences).