I have shortcuts not working either, beside some drag and drop not working anymore. Sometimes if i change the workspace and go back to my favorite workspace, they work again. SOMETIMES. This is really messed up, it just happened with the last strange update they forced.
Also were are the selectors (V and A sliders at the left of this picture from internet). They disapeared, and i suspect it's part of the problem since now i cannot use the clip selection shortcut "d" in my timeline... What's going on, Adobe ?