Same issue including with new files and older files. Happens every session since the last update. This is very obvious to me related to the update and never had this issue before. Same clips even and various formats including Prores and mpeg. Thought it might be a graphics issue but there is not lockups other than Adobe Premiere all other apps working fine.
Create a graphic such as text or a box and later try to move or resize and like clockwork it goes unresponsive.