Your question is how best do I uprez my footage. And Ann's answer is as good as it gets. But I'm partly curious as to what you have done to make that process easier.
What do you actually have? What is the pixel resolution and framerate of the file? I'd look at it with MediaInfo in tree view.
Are you going to have to crop to get the display aspect ratio you need? Or was it shot with this in mind? I assume it is not 16:9. And some digitizers will put the full frame of the film scan into a 16:9 container (with black bars top and bottom or left and right). And to use it in an edit, you have to uprez A LOT to get to the actual footage you want.