I think the answer to that will be that it is not possible.
Using filtering I understand that it is possible to open responsive help with a fllter applied. How was covered elsewhere in the forum quite some time ago. However, once the user is in, they can remove the filter. Even to do that would require a different URL for those who are to see the full help and those who are to see the filtered help.
I rather think the solution will be that when installing your software, the developers need to find a way to apply different URLs and you create different outputs.
See www.grainge.org for free RoboHelp and Authoring information.

@petergrainge
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