If it's the same issue OP described where the mouse has more drawing accuracy, I believe I may have found a fix. In the "Pen & Windows Ink" settings, under the "Additional Pen Settings" pulldown, there's a checkbox for "Let me use my pen as a mouse when it's available." Checking this box seems to have fixed the pen accuracy issue in Acrobat, as it will read tablet inputs with mouse-grade accuracy now. It will still smooth lines, but this shouldn't affect the quality of your marks now.
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