I have the same issue, but only with CS5.5 when I'm using Illustrator. It drives me MAD as I have to then have multiple files and remember which one I really am using/working on. There needs to be a fix for this. I didn't have the issue until Win 10 and just a few months ago. I haven't had the issue with my CS6 versions...yet. PLEASE provide an update to fix this. I am in IT and have checked all permissions, no preview panes...nothing is wrong or abnormal, it just won't let me save over a file. I'll try turning off Google, but I even tried only having the file on the desktop and that didn't work either. I use G-Drive and would think there'd be a fix for this as a number of people use this.
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