I use Illustrator on Windows-based systems. The latest build of Illustrator still has its zoom in/out and hand-panning shortcuts working properly. Ctrl+Spacebar still toggles the zoom tool. I don't see anything in Illustrator's Preferences that look like it could disable the Cmd+Spacebar shortcut. There are options to zoom with a mouse wheel or pinch to zoom on a touchpad. I guess this could be a conflict with OSX?
Yes it looks liek it could be a conflict but I can't work out what that could be. I'm restricted to upgrade from Catalina currently through work - would that be it? None of my colleagues have the same problem though.