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I'm so devastated to know with what adobe product I can draw and color a realistic picture of the mouth like this? I tried illustrator but the mesh tool doesn't seem to the best tool to make the colors! if you wanted to make sth like this what would you use?
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Anything involving airbrush/soft brush work is much more easily achieved in Photoshop.
It's possible with Illustrator, but not easy, especially if you're not already practiced in advanced techniques. If I had to produce that, I'd start in Illustrator to build up the basic shapes, then move it into Photoshop for "painting".
Just remember that once it's in Photoshop, it's resolution-dependent, so be sure to work at a size that will facilitate the final output size.