I'm not so sure the margin is a property of the printer. None of my printer settings (printer Properties in Windows, or hardware settings on the printer's front panel) have a settable margin. Depending on the printer model type, the text will print to within 0.2" - 0.3" of the edge of the paper, but that's a hard limitation--not changeable. Anyway, I found another way to do mostly what I want, i.e. to print a larger doc image (by shrinking the margins & thus making room for expanded text size) of each 8.5 x 11 PDF in a 2-up image per page of paper. My Xerox Phaser printer allows specifying custom-sized paper. So, for a 2-up side-by-side 8.5 x 11 image on Legal paper (8.5 x 14), I define a "Big Legal" size of 10 x 14.3." The printer, then gets fooled into thinking it has more paper size to work with, so it prints further to the edges and thus expands each page image resulting in larger sized text. It'll print to within about 1/2" of the edge of the paper this way. Unfortunately, I can't reduce the space between the 2-up images this way, so I have to put up with the PDF-defined right and left margins in the middle of the 2-up page. I wanted to get the page images all the way to within 0.2" of the paper edge, but I can't increase the Legal size any more than about 10 x 14.3 or my Xerox will think it has to Tile the printout, using 4 sheets of Legal paper. Anyway, since so many software application manuals are no longer delivered as a hard copy with the product, it's nice to be able to print a 2-up copy from the PDF with text that is moderately expanded and thus large enough to read. Obviously, a 2-up printing saves considerably on paper and somewhat on toner, also.
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