replace mobo, cpu, ram and keep drives?

I have a custom built computer ( fractal design case … big size ). Is about 6 years old. Basically it is choking sometimes and I have to use proxies.

I have SSD for OS and programs

another drive for source material (raid 0 HDD x 2)

another drive for cache ( ssd)

another drive for exports ( HDD)

basically what I want to do is replace mobo, cpu, and ram so it is faster more powerful and less prone to proxy doing 4k.

everything is full HD only... monitors and exports.. but new stuff ( 4k h264 for example) is lagging without proxy.

I want to avoid making dnxhr sq proxies, and have stuff work OK.

Is this even POSSIBLE ??  Can you replace a mobo and cpu and ram and KEEP your drives and programs and all the other stuff intact ? Without any loss of data ??

duh...

thanks.

Rod