Set specific layer to Never Print using JS

The print setting, as well as many other OCG properties cannot be accessed from JavaScript.

Whenever I have to do a task like this I write a simple plug-in to perform the single task. Usually using JavaScript parameters.  Then activate the plug-in from my script with a menu item. In fact I wrote a plug-in for modifying several OCG parameters that are not available from the Acrobat UI.  You'll find it here (along with lots of other cool stuff): www.pdfscripting.com