Font Licensing

Hi, I'd like to learn that is the Adobe Fonts (Typekit) grant us a world-wide license to use the font commercially? Is their a restriction in the usage in different region? For example, I live in U.S. and I use the fonts from typekit in my design—may be printed or digital, finally my design work will be use commercially worldwide instead of only in U.S., how should I license the fonts? I have this questions because when I am in the adobe pages, there is an option in the bottom of the page ask me to choose the region, so that's why I am wondering about this. Many many thanks.