A.M.E. Queue Hangs On Second Video Every Time

I'm having a consistent, repeatable issue with Media Encoder queues.   I'm creating queues of 2-6 videos, each 8k x 8k sequences rendering to 4k x 4k ProRes 422. The first video renders fine, somewhere between 2-4 hours. But the second video starts and then shows render times in the dozens to 100+ hours. It doesn't crash or hang per se, but the render times are absurd. I stop the render, restart the PC, open AME and reset the queue, then the render time is back to 2-4 hours. Once the second video in the queue starts, the same thing happens and I have to restart again, so it's not really a queue. I'm guessing there is some issue w/ the system not clearing / resetting VRAM or another system resource. I have nearly 100 videos like this to render, and my system is Windows 10, Media Encoder v14.5 (Build 48), PP v14.5.0 (Build 51), i9 7900x, 128GB RAM, 1080ti w/ 12GB VRAM, SSDs & NVME drives.