How to connect to remote database from AIR App

I am developing an AIR mobile application. I am using Sqlite as my local database. Now I have to maintain some datas in a centralised database which has located in remote server ie., i have to push some data to remote database from my mobile application as well as retreieve.

My questions are

1. Can I use sqlite as centralised database?

2. How can I connect to the database located in server.

Thanks in Advance.

Note: I am using Flashbuilder 4.7 as IDE, using Actionscript3