How to combine drawing and film

Hello all,

I'm not sure whether this is the right forum, but here goes. 

I'd like to make a film that combines digital drawing with film. 

The film will be approx 20 minutes long featuring a drive along a section of motorway/freeway. 

I would like to create a selection of 3D digital interventions as I drive along such as bridges, various drawn shapes. 

My question is this: which programme will best suit me?

I've included a few images to give you an idea of what I'd like to produce....