ColdFusion 10 Update 18 breaking web service calls

After applying ColdFusion 10 Update 18 I'm finding that calls made into any web services that I have within my application fail to reach the target. Using IIS for my web server. I have removed and re-added my connectors using wsconfig.exe. The web sites work fine but the web services I have within the application are now unreachable (error is that the 'remote server cannot be reached'). Is there some other configuration that I will need to do to make Update 18 work for me? If I roll back to Update 17, everything works again.