Local site working for days.  Had to restart computer for Updates.  Server starts fine and http://127.0.0.1:8500/CFIDE/administrator/index.cfm works fine still. 

But now site under root http://127.0.0.1:8500/ initally was getting a file not found error for say /test/1.cfm

Now I'm getting

Could not find the ColdFusion component or interface /Applications/ColdFusion10/cfusion/wwwroot/Application.cfc.  for say file.

Absolutly nothing has been change other than I had to restart computer. I've tried several restarts.  Cleared Cache.

Thanks for any help.