problem with <cfqueryparam list

Hi guys can any one tells me what wrong here I have list and I want to updated the error I get is ( Syntax error (comma) in query expression 'bizname=?,?'. ) it is list from form and it is , delemeted, so whats wrong here check the code, any suggestion greatly approciated.,,, Update biz SET validclient = 1 where bizname= (param 1) , (param 2),,,,