Not able to open Dreamweaver on Big Sur Mac OS 11.01

Creative Cloud compatibility with Big Sur.

https://helpx.adobe.com/download-install/kb/macos-big-sur.html

Please ensure your computer meets or exceeds the minimum system requirements to run Creative Cloud + OS + all other apps you use. Check each one.
- https://helpx.adobe.com/creative-cloud/system-requirements.html

• Did you use the Adobe Cleaner Tool to wipe all old 32-bit apps off your computer BEFORE you upgraded your OS?  If not, I suggest your run it now.  It may not get rid of everything but what it doesn't get you can remove manually.
  https://helpx.adobe.com/creative-cloud/kb/cc-cleaner-tool-installation-problems.html
• Restart your computer.
• Install the latest Creative Cloud Desktop App followed by the latest versions of other CC apps.
• Restart your computer again.

Hope that helps.

Can you this KB article and recreate the user config folder and cache files: https://helpx.adobe.com/dreamweaver/kb/troubleshoot-javascript-errors-dreamweaver-cs6-cc.html ? If that doesn't work you can try to reinstall the product.  And as a last resort, try logging in as a different OS user and confirm there is no user account corruption?