Error #2044: Unhandled securityError:. text=Error #2048: Security sandbox violation: http://fuse-client.mirra.io/fuseclient.swf?gid=266 cannot load data from about:blank. what does this mean?

It's a mistake Microsoft made in using the debug version of Flash Player in their update. They are working on a fix, and have this article to tell you have to revert to the version from last week:

https://support.microsoft.com/en-us/kb/3087916