I have malware in my computer disguised as "Adobe Flash Player."

How do I remove it?  I've tried Avast, hitmanpro, malwarebytes, and Revo uninstaller, the problem remains: Every time I change from one window to another, the same box pops up at the bottom of my screen: "This webpage wants to run the following add-on: 'Adobe Flash Player' from 'Adobe Systems Incorporated'."  This virus also seems to be associated with Java and Oracle.  It interferes with my playing video clips on some (not all) sites -- I get a message saying "Most Recent Version of Adobe Flash Player required."  But I know I HAVE the most recent version, I just downloaded it direct from the Adobe website, after uninstalling everything "Adobe" in my program directory.