Error 16 following uninstalling and reinstalling Acrobat DC (per program request). What do I do to get a clean install?

Error 16 corresponds to file permission issue and steps mentioned in the link I provided are helpful in some cases.

In this case we should try to assign permissions to whole Adobe directory. Please follow the steps as mentioned below depending on your operating system.

Mac

1) Navigate to following locations and assign the current user full permissions to adobe folders. To navigate open finder and click go from menu bar at then click goto.. type /Library/application support/   and click go.

2) To assign the permission right click on adobe folder and click Get info.. A property window will open. Then click on lock symbol to enable editing. Then click + sign to add your username. Then change read only to read and write. Then click gear symbol at the bottom and click apply to enclosed items and click ok..

Windows

1) Navigate to following locations and assign the current user full permissions to adobe folders.  (Right click on adobe folder select properties then click security tab , click edit and select current user you are signed in with , select full control , click apply and then ok)

    C://program data (enable view hidden files to see this folder)

    C://program files 86x/common files

    C://program files 86x/

    C://program files/common files

    C: //program files/

2) try to launch adobe application then

changing permission should look similar to below image

You can refer to following link and discussion for this issue.

Configuration error | Adobe Creative Cloud, Adobe Creative Suite 6, 5.5, and 5

Error 16 is stopping me from working completely

error 16

Error: 16

Hope this helps!