Color Handling with GPU Performance broken on Mac

Going through a rebrand and developing a new color pallet. I have never had an issue before Ai24.

I have 2 external monitors (Asus VC279) and my

MacBook Pro (15-inch, 2017)

Radeon Pro 560 4 GB

Intel HD Graphics 630 1536 MB

Of course I never expect perfect color matching between the screens but Ai is drastically oversaturating and shifting the colors with GPU Performance turned on.

I ran through a bunch of tests changing the color handling, recalibrating my monitors, I even have a presentation I created that displays the same color both hex & cmyk in powerpoint correctly between the screens but is drastically different in Ai. 

Here are some examples of 4 scenarios

MBP GPU Perf On: AI left/PPT right

MBP GPU Perf Off: AI left/PPT rightASUS Monitor GPU Perf On: AI left/PPT right

ASUS Monitor GPU Perf Off: AI left/PPT right

The issue seems to only effect color display on the MBP 

Not sure if this is isolated to Ai or if it is effecting other programs as well