Edit-in plugins grayed out

[Frederic5ECC]

Running LRC 13.3 (Camera Raw 16.3) on an M1 Mac. Mousing over an image in Develop mode shows the magnifying glass and I'm unable to access edit-in plugins. Restarts of no help. 

[John R Ellis]

Try resetting LR's preferences:
https://www.lightroomqueen.com/articles-page/how-do-i-reset-lightrooms-preferences/

LR sometimes soils its preferences file, and resetting it can fix all sorts of wonky behavior. That article explains how to restore the old preferences if resetting doesn't help.