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Adobe and Apple have worked closely together to test Adobe® Creative Cloud applications and Adobe Creative Suite 6 applications for reliability, performance and user experience when installed on Intel® based systems running Mac OS X Mavericks. (v10.9). All Adobe CC and CS6 products are compatible, but a few products require updates to the latest builds to work properly.
Adobe Photoshop® CS5, CS4 and CS3 were tested with Mac OS X Mavericks and there are currently no major issues known.