In future: Please include the following in your questions: Adobe product and Version number Operating system and Version number The full text of any Error Message(s) What you were doing when the problem occurred Screenshots of the problem
Adobe Product and version: Lightroom classic Version 10.1 (although I cannot confirm this because I cannot open Lightroom and view the version, I know it is the latest version from early December.
Operation system and version number: macOS Big Sur Version 11.1
The full text of any error message: “Lightroom encountered an error when reading from its preview cache and needs to quit. Lightroom will attempt to fix this problem next time it launches.” I have launched Lightroom a number of times and the problem still persists, which means that Lightroom has not been able to fit it.
What you were doing when the problem occurred: Launching Lightroom