okay . . . I have this somewhat figured out now. The problem came back after restarting. Dell has an app called Dell Premier Color. It messes with color profiles. Every time one of it's profiles is applied and listed as "default" in the color management panel, the problem occurs. I went into Dell Premier Color and then "advanced", under preferences unchecked "load at startup" and so far the problem does not return even after restarts and my calibrated color profile from Spyder4 is working fine. I've also been trying to track down an issue where my screen brightness kept mysteriously decreasing, as well and it turns out Dell Premier Color was the culprit there too. I think when you chose "Adobe Color Photo" profile they try to lower the screen birghtness to make it more photo appropriate which would be fine, if they gave you any indication whatsoever that that setting did that. Two problems fixed . . . stupid Dell!
... View more