Yup, UE5.5.1 and UE5.5 crashes as soon as you enable the plugin.

Fatal error: [File:D:\build\U5M-Marketplace\Sync\LocalBuilds\PluginTemp\HostProject\Plugins\Substance\Source\SubstanceCore\Private\SubstanceCoreModule.cpp] [Line: 157]
Unable to load Substance Library.

0x00000218b3422ffe UnrealEditor-SubstanceCore.dll!FSubstanceCoreModule::StartupModule() [D:\build\U5M-Marketplace\Sync\LocalBuilds\PluginTemp\HostProject\Plugins\Substance\Source\SubstanceCore\Private\SubstanceCoreModule.cpp:161]
0x00007ff82f1147b9 UnrealEditor-Core.dll!UnknownFunction []
0x00007ff8d639a234 UnrealEditor-Projects.dll!UnknownFunction []
0x00007ff8d63b71f4 UnrealEditor-Projects.dll!UnknownFunction []
0x00007ff8d6399ab5 UnrealEditor-Projects.dll!UnknownFunction []
0x00007ff67d86a648 UnrealEditor.exe!UnknownFunction []
0x00007ff67d86dbbe UnrealEditor.exe!UnknownFunction []
0x00007ff67d865566 UnrealEditor.exe!UnknownFunction []
0x00007ff67d86589a UnrealEditor.exe!UnknownFunction []
0x00007ff67d869114 UnrealEditor.exe!UnknownFunction []
0x00007ff67d87bd04 UnrealEditor.exe!UnknownFunction []
0x00007ff67d87f0ba UnrealEditor.exe!UnknownFunction []
0x00007ff90fef259d KERNEL32.DLL!UnknownFunction []