Timeline sync issue on reopen. Footage looses in and out points and defaults to the start clip

Premiere PRO Beta 24.4 (build 23) 
Mac M1 Pro

When i open a project that i have been working on the day prior.  A random selection of files revert my cuts back to the the start of the timecode. loosing the in and out points. 
resulting in the timline with my two cameras getting out of sync. 

I am working on a two camera setup that has had files synced with a Tentycle Sync. 

Not sure how to explain this better.  The files are linked, (no Missing media error) but the clips have a greyed out lines over them. 

I understand this is common with clips that have different frame rates.

Which i know is not ideal but it happened in this instance. Trying to make the best of it. 

And help or trouble shooting would be a great help. 

the issue also effects when i try and export with Media Encoder. and the sync on all my files is off. 
If i export within Premiere Pro it works fine.