Are you happy using Adobe, Blender, Autodesk or some other manufacturer to make an animated cartoon?

Yes, I am very happy using Adobe.

Since you included Blender Foundation (the publisher of Blender) and Autodesk, I'm guessing that the YouTube animated cartoon about the rock band is going to be 3d rather than 2d.

Here's an overview of software that can be used for producing a full season of an animated 3d cartoon:

• Production budgets can be done in Microsoft Excel or Entertainment Partners Movie Magic Budgeting.
• Scripts can be written in Final Draft.
• Storyboards can be drawn in Toon Boom Animation Storyboard Pro, Adobe Animate, Adobe Photoshop, or CELSYS Clip Studio Paint.
• Dialog recording and sweetening can be done in Avid Pro Tools or Adobe Audition.
• Rough cuts can be assembled in Toon Boom Animation Storyboard Pro, Adobe Premiere Pro, or Avid Media Composer.
• 3D characters can be created in Maxon Cinema4D, Autodesk Maya, Maxon ZBrush, or McNeel Rhinoceros, but there are quite a few options for conception, modeling, texturing, rigging and skiing, and animation.
• 3D environments can be created in Maxon Cinema4D or Autodesk Maya but like 3d characters, there are quite a few options.
• 3D scenes based on the rough cuts can be animated in Maxon Cinema 4D or Autodesk Maya but like the 3d characters and 3d environments, there are quite a few options.
• Custom textures for 3d models can be created in Adobe Photoshop.
• Several 3D scenes may go to Adobe After Effects for visual effects and/or 3d finishing.
• 3D scenes are likely to be assembled in Adobe Premiere Pro or Avid Media Composer.
• The score for the fine cut can be mixed in Apple Logic Pro, Steinberg Cubase Pro, or Ableton Live.
• The sound mix of the fine cut can be done in Avid ProTools with stems being imported back into Adobe Premiere Pro or Avid Media Composer.
• Review and approval can be done with Adobe FrameIO.
• The edited full-resolution file can be exported from either Adobe Premiere Pro or Avid Media Composer with audio channels configured based on distribution requirements (for YouTube, this would be a stereo mix).
• If not delivering a ProRes or DNx full-resolution file (MOV or MXF), encoding to a delivery format like H264 or HEVC might use Adobe Premiere Pro, Avid Media Composer, Adobe Media Encoder, or Telestream ContentAgent.  YouTube accepts ProRes.  Unless the upload bandwidth speed is limited, use ProRes for YouTube delivery.
• Subtitles for the edited full-resolution file can be done in Telestream Captionmaker or Adobe Premiere Pro.  YouTube's automatic live captioning should not be used and YouTube encourages "creators to add professional captions first".

https://www.adobe.com/creativecloud/animation-software.html