Printing in Colour not working.

Can some please help me.  I have been trying to print an pdf A3 Colour photo print for the last 4 hours and it is not working, it prints but like it is like it is printing a negative.  I have uninstalled and reinstalled Adobe reader but still doesn't work.  I tried printing one of my photos from jpg and this works so am totally baffled as to what is going on.