There is a problem with Adobe Acrobat/Reader. Please exit Adobe Acrobat/Reader and try again.

Yep, old post but here is my fix.

On Windows 10/64bit with Acrobat DC nothing will get it to display in internet explorer except the following:

1. The obvious use Chrome or Firefox and this does not happen.

2. If you need to use IE; Log in as administrator on the local pc or log in as administrator@yourdomain.com. Go to internet options, Advanced tab, Reset include check for removing personal settings. Restart IE and test. If it does not work the first time do it again. One thing I notice is if I dont get a CMD window to pop up during reset it has not worked properly and acrobat will not opent he document in IE.

PLEASE NOTE: I dont know why but if I log in with any "admin" or "domain admin" account this does not work. I have to log in as the PC admin if not on a domain (as in Administrator typed that way) or the administrator@yourdomain.com account. No clue why but this works EVERY time and nothing else works.

I tried the following and it worked for me.

1) Unistall Adobe Reader

2) Rename all Adobe folders under

        C:\ program files

        C:\Documents & Settings\UserID\Local Settings\Application Data

        C:\Documents & Settings\UserID\Application Data

3) Re-install Reader

Please note the "Local settings" and "Application Data"are hidden.

Hope this helps:)

Cheers        

Pop-up blockers.  In our case, the google toolbar

with pop-up blocker enabled, then disabled.  This prevented

the pdf from a web site to be opened up in a new tab or window.

We disabled the google toolbar and we were back in business.

Hope this helps.