Editorial workflows with assignments and sign-offs

My company is new to Adobe online. We'd like to be able to accomplish the following, but we're not sure if it's supported by any of the Adobe cloud products. Here are our needs:

1. Upload a PDF document to the cloud
2. "Assign" that document for editorial review (annotations) by a particular individual. Even if this isn't directly supported, how might we achieve it?
3.  When that individual is done making annotations, they "assign" it to someone else
4.  Request "sign-off" or approval from any individual
   
   Everyone working on the document is a licensed user in our organization, if that helps.

Thanks in advance!