The most common cause of breakup problems is having the buffer sizes set too low. That's in Preferences>General>Audio Hardware. But the closer you get to the minimum spec with a machine, the more you have to turn off in it to get any acceptable performance at all. Primary suspects are Wifi polling, and anti-virus software...
Alright, this WAAAAYYY helped me out:
The partition, AA was running on, didnt have its own virtual RAM and Windows always took Audition its virtual RAM away, its temporary memory.
SOLUTION:
System -> advanced System Settings -> Performance Options -> Advanced -> Virtual Memory -> change
Now manually set your Virtual Memory. (Windows doesn't need too much, I gave it 3000-6000 MB and another 3000-6000 for my other partition, on which AA is running.) A maximum of about 1,5 x physical RAM is perfect for me. This solved all my lagging, recording and crackling problems.
SOOOO: No more skipped samples but only fast recording and playback.