Two puzzling technical issues

I'm running into a couple of problems:

1. (This one has happened to me many many times): I go co close Audition. It asks me if I want to save all unsaved changes. I click yes or yes to all, but no matter what I click, even if I click no, the program will not close. the only way I can get out is to cancel it through task manager, and of course I've lost a lot of work, though I never know exactly how much.

2. I save my file, as I do often. Then it starts trying to export the work to ... I don't know where, but that's inevitably followed by the message "The file is in use by another application and cannot be overwritten."

Both of these problems often recur even after I reboot the whole system.

Any insights would be greatly appreciated.

Thank you