Setting resolutions for an elearning lesson

Someone once told me you should have the PC screen set at Resolution X and then make sure when you record from Captivate also have it at this resolution X so they match.

I am using 1024 x 768 on both PC res and Captivate Recording to create a suite of lessons.

I know that previous posts have talked about finding out the main corporate screen settings for monitors and working from there.

In the modern world of working, is there a one size fits all solution that you can apply to captivate lessons that will mean whatever platform you choose to present the lesson , it will always look acceptable.  Of course I am aware that you can publish specifically for ipads

I know that users also have various assistive  technology tools to make any pre written eLearning at a better size for them to read the screen if the lesson size is too small for their existing eye sight condition.  As most lessons are run in the Browser environment , apps such as Jaws And Dolphin SuperNova should cope very well with magnifying the lesson if required.