3d mesh no longer has hi res maps (details)

every once in a while as i am texturing my 3d mesh I will lose details or the "HI REZ". this happens in one of two ways, 1. I will apply an effect or add detail to an existing layer, 2. Or I will close the application and come back another day and once I open the project the model will no longer have the HI REZ look even though it will still have the HI REZ maps still baked. Is there any suggetions or tips anyone can provide to assist me moving forward?

This Image is the result of me coming back and reopening the project.