Framemaker can't write to disk

When I try to save my Framemaker file I get an error message "Framemaker can't write [name of file] to disk.

The file is not locked, I'm not working on a network, there's plenty of disk space where I'm trying to save it.

I was able to save that same file previously but after working on it for awhile, it refuses to save.

I tried saving it with a new name, I tried saving to a different location on my computer, but still get the error message.

It's a large file so I'm guessing that might be the problem.

Does Framemaker have a file size limitation?

Would there be some other reason for the error message?