How can I take two column in a page in Frame Maker?

The intent is unclear here:

• Make a page 2-col?
• Make part of a page 2-col?
• Remove 2-col from a page?

You define column numbers on the master pages. So you go to the master pages and use Format->Page Layout->Column Layout and set the desired number of columns. You can use Object styles for anchored frames to quickly adjust them. If you want to have multiple columns on the fly, you can also apply an object style to the text frame on the body pages.

You want to make a page with 2 columns? I suggest you invest in a copy of Matt R. Sullivan's Unstructured Framemaker 11 (it's old, but the basic concepts haven't changed) - I think this would really help you work with FM.