Can't open Illustrator. I receive code 224 and a message saying I can't use Illustrator at this time.

Hello ​@TR_ISWEP 

Sorry to hear about the experience. Licensing and activation issues are often resolved by a few targeted steps, so let's narrow it down. Hopefully, Dave’s earlier suggestions helped; if not, this help article walks through the most common fixes:

https://helpx.adobe.com/download-install/kb/troubleshoot-licensing-activation.html

Please try the steps in order and share what you observe - including which step you got to and any error messages along the way. If this resolves the issue, kindly mark the helpful reply as the correct answer to help others searching for the same fix.

Anubhav

Has this version always done this or did it just start? 

What OS, OS version, software version?

Did you uninstall and reinstall?