Hand Tool Space Bar not working

Most probably one of these interfering: 

• WebRoot
• Apple Terminal
• Word, Excel, Powerpoint
• »Enable Full Keyboard« in Settings > Accessibility > Keyboard on Mac OS
• Apple Mail, Outlook
• Spacebar is used as a shortcut by the system
• Chrome, Internet Explorer, Safari
• Wacom Desktop Center, Wacom settings
• Windows Touch Pad problem
• LastPass, Bitwarden (password managers)
• The VPN