Illustrator will not start on my work PC anymore - "Requires the preferences folder to be reset"

I am the IT guy posting on Kims behalf - we are using 3 windows PC's that was built for 3 seperate graphic designers. All of the PCs are the same. All 3 of the PCs have the same exact issue. No other adobe app in the entire suite (they use a TON of adobe programs) has this issue. I have performed all of the expected troubleshooting that Adobe gives - plus another 10 lbs from what the internet tells me. Nothing has budged it. The only common factor between these 3 people other than that their PCs are the same, is that they are all not using an admin account within our domain. They are just standard user accounts. So, since they are user accounts, now we know they dont have FULL ACCESS to the hard drive/SSD/OS Drive. Nor any drive. For safety reasons, and for preventative issue reasons as well. Not that this stands in the way of anything, because every other Adobe app opens up. I don't mean to make that seem serious either - they literally are 1 step under full access. They just don't have the full access button selected on the permission box. So these people have more than enough access granted to each and any drive necessary to work. We are just stumped and forced to resort to illustrator on the web, which all 3 of the designers absolutely hate.