Hey again Mike,
I get all of my used vectors directly from Fotolia, so I doubt an infection to be honest.
As prevoius stated my collegue is on mac and has the same Problem (it's even a bit worse on his end).
I'll try to reset the Could OOBE and let you know if something changes!
UPDATE:
I removed the opm.db File as you suggested and it actually had quite the Impact on the testfile I uploaded earlier, so it seemed to work!
Althought I noticed something wich might put the case to a rest.
I tried working on another file wich is packed with different Vector files and noticed a rather big difference in Speed while trying to edit different vectors within the same file. Now I'm starting to think that it's just a Problem with how the vectors are built.
To specify the Thing I noticed, I uploaded another testfile for you to check out:
https://drive.google.com/open?id=1CMM5gr-GT5fVT1bvCcZwZqzk_-BPWHyM
Some of the Vector files within this document work like a charm but the Pineapple for example is notably slower in everything I try to do with it.
So Maybe it's just those specific vectors, wich are packed with alot of gradiants and anchor Points wich cause the slowdown of the Overall Performance?
Thankuyou for sharing a file, this helps so much to be able to offer you help.
Firs your image size is very large.

Do a Save as and turn off pdf compatible and you will save 100mb. The 2nd file you posted, still runs fast on my computer I never had to wait moving and transforming opbjects

I see you are working in RGB, is the final destination for this to be a digital image? If not and for print you need to change to CMYK. For this of art, I would work in photoshop. You have many vector paths that are adding an organic look.

The illustrations have an air brushed look that photoshop brushes are ideal for. I rasterized the pineapple to show you this looks good as bitmap.

Starting from scratch I would paste your Fotalia vector art into Photoshop and rasterize each as a layer (or smart object, if you plan to for example removed one grape).