Screenshot colours change appearance when saving as PDF, but spot colours don't.

Question

Screenshot colours change appearance when saving as PDF, but spot colours don't.
When I screen shot an image and paste it into Illustratrator the colour is matching the original.
I can use my colour picker tool to exstract that colour and fill my vector object.
The problem comes in when I save the document as a PDF file, close and open up. It is then when the screen shot colour change. But the vector colour is still the original colour.
I have checked 3 other exact same Macbook laptops, with the exact same settings and ALL colour profiles.
All the other Macs seem to be have no issue. Only mine change.

We are all running on the exact same Macbooks and versions of Illustrator.
Note that if I change the document colour mode to RGB from the beginning to end of this process. The colours do not change. Unfortunately we work in CMYK mode.

Ton Frederiks · Answer

I would turn on in your Color Settings the checkboxes for mismatched and missing profiles. That will give you a warning and a choice when profiles do not match.

What it the RGB profile in your Color Settings? Do you place screenshots or drag and drop them?

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