Substance 3D Sampler Crashes After Splash Screen

Hello, I’m running into an issue with the Substance 3D Sampler being unable to get past the splash screen. I’ve tried the latest version, version 5.0, and one of the 4.X versions and had the same issue on all of them. Until today when I immediately ran into the issue, I don’ think I had ever installed or launched Substance 3D Sampler before, and I did restart my PC between installations for both Sampler and Nvidia drivers.
I tried deleting the contents of C:\Users\username\AppData\Roaming\Adobe\Adobe Substance 3D Sampler as mentioned in this thread,

but the issues persisted.
Here are some hardware/software specs as well as my log file.
AMD R9 7950X3D, RTX 5080
Using the latest Nvidia studio drivers, version 591.74
Windows 11 Pro 25H2 , OS build 26200.7623