help please

Even though Sequoia is supposed to be compatible with many Adobe apps, there have been many issues reported.

You may want to roll back and wait a while before updating.

https://helpx.adobe.com/download-install/kb/macos-sequoia-compatibility-common-issues.html

The message suggests reinstalling Photoshop. Have you tried that already, or are you unable to because you can’t find the Creative Cloud desktop app/installer?

If you can’t find the Creative Cloud desktop app, you can download it from here and reinstall it, then reinstall Photoshop:

Download Creative Cloud

Another way to approach this is to look where that default keyboard shortcuts file should be. The folder paths to most settings files are listed on this web page:

Preference file functions, names, locations | Photoshop

That page says the default keyboard shortcuts file should be at:

/Users/[user name]/Library/Preferences/Adobe Photoshop [version] Settings

Is the default keyboard shortcuts file present there, or missing? If you have trouble finding the Library folder, see:

Can't see user library files in macOS