Instagram Stories GIF stickers look pixelated

I recevied this response below from GIPHY support which I will try and then report back here in case anyone else can use this info. —Laurie

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Our applications do optimize the content for size, which sometimes results in subtle changes to the GIF's quality, size, and speed. We're constantly refining this, and your feedback has been added to our development queues.
 
In the meantime, please check out the feedback from our design team below:
 
1. Defringing the layers (Layer - Matting - Defringe). This is a little tedious since it's frame by frame, but can help a lot.
2. Make sure there are no semi-transparent pixels lingering around the edges of your sticker.
3. If working in Photoshop - Save for Web Legacy and set the Matte setting to None. This way it won't default to white edges, and will leave a more natural edge. It helps reduce the 'halo' effect.
4. If your sticker has a black outline set the Matte to black.5. For things that need to be semi-transparent (spray paint, or sparkles etc) turn ON diffusion transparency and adjust the % amount as you see fit.
6. Focus on the largest resolution with the fewest amount of frames (obviously this depends on your animation style)