Is it possible to move a selection using absolute coordinates in a script?

Agree with @Stephen Marsh. In scripts, such restrictions are not a problem. It is enough to get X,Y of any one point of the selection or object (top, bottom, right, left, center) and find the difference in X, Y between where this point should be after moving. These are relative move values that can be passed to the move function.

Good question! Even the DOM uses relative values for transform or selection.translate() etc.

If you know the target X,Y position, then you can obviously calculate the relative difference for the transform.