Photoshop become completely unresponsive after use.

So using Photoshop recently i've noticed after I start using the program for five minutes the whole program becomes unresponsive. I am able to "Switch Tools" but i am unable to actually use them.... almost like the whole canvas is just locked. I cannot move around it, and it stays frozen in one area. The only thing I can do ironically is save. Once I close the window, and reopen it IO can work back into it for another five minutes and the cycle repeats.  After using this program for 10 plus years I cannot pinpoint what is actually wrong with this.

Any ideas of what I can do? 
I use Photoshop professionally and this is a HUGE set back for me.